System review
Evaluate formulation, propellant, components, methods, specifications and device history.
PRESSURIZED INHALATION MANUFACTURING
Metered Dose Inhalers
A dedicated pathway for pressurized inhalation products that integrates formulation, components, filling, assembly, testing and commercial execution.
REF. JV-MDI-001PLATFORM OVERVIEW
Pressurized inhalation requires the product, process and device to work as one system.
Metered dose inhaler projects involve more than filling a formulation into a canister. Product performance depends on formulation behaviour, component compatibility, filling controls, assembly and repeatable dose delivery.
Jean Vichar’s MDI pathway begins with a structured review of the formulation, propellant system, canister, valve, actuator, analytical package and intended market. The final project plan is defined after these interdependencies are understood.
Formulation and propellant systemAssess available development knowledge, material behaviour and relevant controls.
Canister, valve and actuatorReview the selected component configuration as an integrated delivery system.
Filling and assemblyDefine process steps, controls and documentation needed for repeatable manufacture.
Performance testingAlign agreed testing and acceptance criteria with product and market needs.
REF. JV-MDI-002DEVELOPMENT TO COMMERCIALIZATION
Transfer strategy
Define the knowledge, materials, methods and process parameters required for transfer.
Process confirmation
Establish filling, assembly and control steps suitable for validation and routine execution.
Commercial support
Coordinate production, quality review, packaging and ongoing technical management.
REF. JV-MDI-003PARTNERSHIP VALUE
One coordinated workstream
Formulation, device, process and quality activities are considered together rather than as disconnected tasks.
Early technical visibility
Component choices, test requirements and documentation gaps are identified before they affect scale-up or registration timing.
Lifecycle perspective
Future supply, component changes, packaging and technical updates are considered beyond the initial batch.